|
Widely patent fontanelles and sutures
|
0.100 |
Biomarker
|
phenotype |
HPO |
|
|
|
|
Vesicoureteral Reflux 1
|
0.050 |
GeneticVariation
|
disease |
BEFREE |
AGTR-1 1166A/C polymorphism is associated with occurrence, but not progression, of VUR.
|
25939993 |
2015 |
|
Vesicoureteral Reflux 1
|
0.050 |
GeneticVariation
|
disease |
BEFREE |
This study was designed to evaluate the angiotensin-converting enzyme insertion/deletion (ACE-I/D), angiotensinogen (AGT) M235T, and angiotensin II receptor type 1 (ATR1) A1166C and type 2 (ATR2) C3123A gene polymorphisms as risk factors for progression to ESRD in patients with VUR.Methods.
|
19288324 |
2009 |
|
Vesicoureteral Reflux 1
|
0.050 |
GeneticVariation
|
disease |
BEFREE |
The M235T polymorphism of the angiotensinogen ( ATG) gene, the I/D polymorphism of the angiotensin converting enzyme ( ACE) gene, and the A1166C polymorphism of the angiotensin II type 1 receptor ( AT1) gene were identified in 77 patients with primary VUR (aged 6.9+/-3.2 years, mean+/-SD) and 80 healthy controls (aged 33+/-7 years).
|
12478352 |
2002 |
|
Vesicoureteral Reflux 1
|
0.050 |
GeneticVariation
|
disease |
BEFREE |
The distribution of the AT1 receptor genotypes was no different between patients with VUR and healthy controls.
|
10233502 |
1999 |
|
Vesicoureteral Reflux 1
|
0.050 |
GeneticVariation
|
disease |
BEFREE |
We studied the angiotensin-converting enzyme (ACE), angiotensinogen (AGT), and angiotensin II type 1 receptor (AT1R) gene polymorphisms for association with susceptibility to primary vesicoureteral reflux (VUR) and disease progression in 74 Taiwanese children, including 16 with end-stage renal disease (ESRD), and 117 normal controls.
|
15045574 |
2004 |
|
Vesico-Ureteral Reflux
|
0.020 |
GeneticVariation
|
disease |
BEFREE |
We studied the angiotensin-converting enzyme (ACE), angiotensinogen (AGT), and angiotensin II type 1 receptor (AT1R) gene polymorphisms for association with susceptibility to primary vesicoureteral reflux (VUR) and disease progression in 74 Taiwanese children, including 16 with end-stage renal disease (ESRD), and 117 normal controls.
|
15045574 |
2004 |
|
Vesico-Ureteral Reflux
|
0.020 |
GeneticVariation
|
disease |
BEFREE |
The aim of this study was to establish the relationship of selected polymorphisms: 14094 polymorphism of the ACE, polymorphism rs1800469 of TGFβ-1, rs5443 gene polymorphism of the GNB3 and receptor gene polymorphism rs5186 type 1 AGTR1 with the occurrence of the primary vesicoureteral reflux.
|
27988909 |
2017 |
|
Very Low Birth Weight
|
0.020 |
GeneticVariation
|
phenotype |
BEFREE |
Angiotensin II type 1 receptor A1166C polymorphism and prophylactic indomethacin treatment induced ductus arteriosus closure in very low birth weight neonates.
|
12904590 |
2003 |
|
Very Low Birth Weight
|
0.020 |
Biomarker
|
phenotype |
BEFREE |
The aim of the present study was to investigate whether genetic polymorphisms leading to lower angiotensin converting enzyme activity (ACE) or impaired functionality of angiotensin II (AII) type 1 receptor (AT1R) might predispose very low birth weight newborns (VLBWs) to the development of acute renal failure (ARF).
|
11793101 |
2001 |
|
Ventricular Remodeling
|
0.200 |
Biomarker
|
phenotype |
RGD |
Exercise training combined with angiotensin II receptor blockade limits post-infarct ventricular remodelling in rats.
|
18252761 |
2008 |
|
Ventricular hypertrophy
|
0.010 |
Biomarker
|
disease |
BEFREE |
AII has also been implicated in the development of cardiac hypertrophy because angiotensin I-converting enzyme inhibitors and AT1R antagonists prevent or regress ventricular hypertrophy in animal models and in human.
|
10639182 |
2000 |
|
Ventricular arrhythmia
|
0.030 |
GeneticVariation
|
disease |
BEFREE |
The frequency distribution of the ACE and AT1 receptor gene polymorphism and their possible relation regarding malignant ventricular arrhythmias in patients with coronary artery disease (CAD) and left ventricular dysfunction was determined.
|
10615414 |
1999 |
|
Ventricular arrhythmia
|
0.030 |
GeneticVariation
|
disease |
BEFREE |
We evaluated 485 patients with chronic HF to see whether the angiotensin receptor type 1 (AT1R) 1166A/C or angiotensin-converting enzyme insertion/deletion (ACE I/D) polymorphisms were associated with a higher rate of ventricular arrhythmias requiring implantable cardioverter defibrillator (ICD) therapies over a 5-year period.
|
22939041 |
2012 |
|
Ventricular arrhythmia
|
0.030 |
Biomarker
|
disease |
BEFREE |
Since excessive QT prolongation is a major risk factor for ventricular arrhythmias and sudden death, we hypothesize that chronic stimulation of AT1R might contribute to sudden death by promoting delayed repolarization and ventricular arrhythmias.
|
18245065 |
2008 |
|
Venous retinal branch occlusion
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
At the multiple logistic regression analysis, the adiponectin +275 T allele carrier and AGTR1 1166 C allele carrier status were found to be associated with an increased risk of BRVO (TT vs. GG and TG: odds ratio = 2.278, P = 0.002, 95% confidence interval: 1.370-3.789; CC vs. AA and AC: odds ratio = 1.804, P = 0.025, 95% confidence interval: 1.079-3.017).
|
25932559 |
2015 |
|
Vasovagal syncope
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
No significant AT1R antibody activity was found in the subjects with vasovagal syncope or healthy subjects.
|
29618472 |
2018 |
|
Vascular inflammations
|
0.020 |
Biomarker
|
phenotype |
BEFREE |
Perivascular Adipose Tissue Angiotensin II Type 1 Receptor Promotes Vascular Inflammation and Aneurysm Formation.
|
28760942 |
2017 |
|
Vascular inflammations
|
0.020 |
Biomarker
|
phenotype |
BEFREE |
AT1R antibody and inflammatory cytokines may identify those at risk for renal vascular inflammation and lead to early biopsy and intervention in pediatric kidney transplantation.
|
28927645 |
2018 |
|
Vascular Diseases
|
0.030 |
GeneticVariation
|
group |
BEFREE |
The A1166C polymorphism in the angiotensin II receptor, vascular type 1 (AGTR1) gene has been associated with a range of vascular diseases.
|
17586781 |
2007 |
|
Vascular Diseases
|
0.030 |
Biomarker
|
group |
BEFREE |
The angiotensin II receptor AGTR1, which mediates vasoconstrictive and inflammatory signaling in vascular disease, is overexpressed aberrantly in some breast cancers.
|
29259013 |
2018 |
|
Vascular Diseases
|
0.030 |
GeneticVariation
|
group |
BEFREE |
Our findings suggested that the angiotensin II Type 1 receptor genotype may influence the clinical expression of vasculopathy in these patients.Functional analyses should follow.
|
27488275 |
2016 |
|
Uterine Fibroids
|
0.010 |
GeneticVariation
|
group |
BEFREE |
Association of ACE I/D and AGTR1 A1166C Gene Polymorphisms and Risk of Uterine Leiomyoma: A Case-Control Study.
|
31554351 |
2019 |
|
Urologic Diseases
|
0.010 |
GeneticVariation
|
group |
BEFREE |
The results indicated that the ACE insertion/deletion and angiotensin II type 1 receptor gene polymorphisms were not independent risk factors for renal scar formation in recurrent urinary tract infection of paediatric patients without uropathy.
|
16109085 |
2005 |
|
Ureteral obstruction
|
0.030 |
Biomarker
|
phenotype |
BEFREE |
The protein expression of GPR40 was decreased, while the Bax/Bcl-2 protein expression ratio, the expression of tumor necrosis factor (TNF)-α mRNA, and angiotensin II type 1 receptor (AT1R) protein were increased in mice with UUO.
|
31295865 |
2019 |